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Conservative treatment of anal lesions in crohns diseases in CD patients has been advocated given the high risk of complications and the evidence that spontaneous healing may also occur. According to these results and literature data, although not randomized, it could be argued a judicious choice of the surgical option in patients non-responding anal lesions in crohns conservative therapies. That is the first and foremost goal that we need to achieve. The method of calprotectin detection has higher accuracy to detect endoscopic activity, compared to other clinical and laboratory indexes. Generally, I refrain from excising them.
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